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Online ISSN:-2455-1732


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Year 2020

Volume: 6 , Issue: 1

Santosh University Journal of Health Sciences

Analyzing Efficacy of AMLEXANOX in Treatment of Recurrent Oral Apthosis

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Author Details: Sanjeev Laller, Mamta Malik, Ravinder S Saini, Divya Vardaini, Meenakshi Sharma, Anjali Ahlawat

Volume : 2

Issue : 1

Online ISSN : 2455-1732

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Article First Page : 18

Article End Page : 20


Background: Recurrent aphthous stomatitis (RAS) is a multifactorial disorder which is common in 20% of society characterized by recurrent oral ulcer in person who does not have other sign of sickness. The aim this study was to evaluate and compare efficacy of anti-inflammatory agent amlexanox and topical anesthetic agent in reducing ulcer size and pain.
Materials and Methods: The effectiveness of healing ulcer measured using two parameters, which are the ulcer size and pain score. Thirty patients (n = 30) with minor recurrent aphthous stomatitis were selected for the study, with no known medical illness. Subjects were divided into two groups. Study group (Group-A) received Amlexanox (5%) and the other control group (Group-B) received topical anesthetic agent. The subjects were required to apply the medication 4 times per day. Ulcer size and pain were been measured on treatment days 1 and 4. Data were analyzed using t test for independent sample.
Results: Significant reduction in ulcer size and pain was noticed in study group (Group-A) as compared to control group (Group-B).
Conclusion: Amlexanox can reduce the ulcer size and pain associated with the aphthous ulcers with no side effects of the drug.

Recurrent aphthous stomatitis (RAS), Oral Apthosis, Amlexanox, Visual Analogue Scale (VAS)

Doi No:-10.18231