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Santosh University Journal of Health Sciences

Comparison of systemic autonomic functions in primary angle glaucoma and in normal subjects

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Original Article

Author Details : Mohammad Monis Khan, Varun Malhotra, Yogesh Tripathi, Usha Dhar, Shivani Gupta

Volume : 2, Issue : 2, Year : 2016

Article Page : 117-121

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The present study was conducted to assess the autonomic activity in 30 normal healthy [control] and 30 Primary Open Angle Glaucoma [POAG] subjects. The studies related to record the autonomic dysfunction in POAG was undertaken. The results showed that both the parameters used for sympathetic as well as parasympathetic activities were found to be statistically highly significant except in the case of resting heart rate. No changes were observed in the normal subjects. The changes in the parameters of autonomic function [i.e. Resting HR, T-wave amplitude, QTc, S/L ratio, Valsalva ratio and Cold Pressor Response] in the present study helped concluding that the autonomic involvement in POAG is present. POAG showed decrease in both the sympathetic and parasympathetic activity. Early detection and treatment of risk factors e.g. cardiovascular factors [systemic hypertension, hypotension], sympathetic and parasympathetic dysfunctions that affect optical circulation, aqueous production and innervations of ciliary body, muscles and processes is essential before irreversible changes set in and effect vision.

Keywords: POAG Primary Open Angle Glaucoma, Autonomic Function

How to cite : Khan M M, Malhotra V, Tripathi Y, Dhar U, Gupta S, Comparison of systemic autonomic functions in primary angle glaucoma and in normal subjects. Santosh Univ J Health Sci 2016;2(2):117-121

Copyright © 2016 by author(s) and Santosh Univ J Health Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (