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Journal of Pharmaceutical and Biological Sciences


Chemical constituents from the Aerial parts of Rumex hastatus D. Don


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Original Article

Author Details : Shahnaz Sultana, Mohammed Ali, Showkat Rasool Mir

Volume : 5, Issue : 5, Year : 2017

Article Page : 179-187



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Abstract

Rumex hastatus D. Don (Polygonaceae) occurs in Afghanistan, Pakistan, India, Bhutan and western China as a small perennial shrub and is used as an alternative, astringent, carminative, diuretic, laxative, tonic and to treat bloody dysentery, bilious complaints, blood pressure, cough, diarrhoea, dysentery, fevers, jaundice, headache, lung bleeding, piles, neoplasm, rheumatism, skin diseases, wounds and throat pain. Phytochemical investigation of a methanolic extract of the leaves led to isolate seven new chemical constituents characterized as 3?,4?-dihydroxybenzyl oleate (2), β-sitosterol 3-benzyl ether 3?-capriate (4), β-sitosterol 3-benzyl ether 3?-oleate (5), β-sitosterol 3-(3?,4?-dihydroxybenzyl) ether 3?-linoleate (6), β-sitosterol-3β-benzyl 3?-oxy-3?-O-β-D-galactopyranosyl-(6a?1b)-O-β-D-galactopyranosyl-(6b?1c)-O-β-D-galactopyranosyl-(6c?1d)-O-β-D-galactopyranosyl-2d-capriate (β-sitosterol 3-(3?-hydroxybenzyl) 3?-O-β-D-tetragalactoside 2d-capriate, 7), 1-undecanoxy-3-phenol-3-O-β-D-xylopyranosyl-(2a?1b)- O-β-D-xylopyranosyl-(2b?1c)- O-β-D-xylopyranosyl-(2c?1d)- O-β-D-xylopyranosyl-(2d?1e)- O-β-D-xylopyranoside (n-undecanoxyphenol 3-O-β-D-pentaxyloside, 8) and ?-L-glucopyranosyl-(2a?1b)-O-?-L-glucopyranosyl-(2b?1c)-O-?-L-glucopyranosyl-(2c?1d)-O-?-L-gluco- pyranosyl -(2d?1e)-O- ?-L -glucopyranosyl-(6e?1f)-O- ?-L –glucopyranoside (?-L-hexaglucoside, 9) together with the known compounds tridecyl oleate (1) and β-sitosteryl linoleate (3). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.

Keywords: Rumex hastatus, Aerial parts, Chemical constituents, Isolation, Structures elucidation


How to cite : Sultana S, Ali M, Mir S R, Chemical constituents from the Aerial parts of Rumex hastatus D. Don. J Pharm Biol Sci 2017;5(5):179-187

Copyright © 2017 by author(s) and J Pharm Biol Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)