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IP Journal of Diagnostic Pathology and Oncology

A five year histopathological study of granulomatous lesions at a tertiary care centre

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Author Details : Atul Shrivastava, Alpesh M. Maru*, Tejas S. Choksi, A. S. Agnihotri

Volume : 3, Issue : 4, Year : 2018

Article Page : 253-256

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Introduction: Granulomas are common findings in biopsy of various organs. Granulomas are a characteristically focal circumscribed collection of histiocytes along with lymphocytes and giant cells.
Objectives: Present study was undertaken to note the frequency and etiology of granulomatous inflammation in various organs by means of histopathology examination.
Materials and Methods: The prospective study was conducted for five years (January 2011- December 2015) in pathology department of a medical college hospital. The study includes total 510 biopsies which were showing granulomatous origin.
Results: Out of 510 total biopsies, largest number 430 biopsies diagnosed as tubercular inflammation (84.31%), followed by leprosy (5.09%), fungal origin (2.74%), parasitic (1.32%) and cases of granuloma of unknown etiology (1.78%).
Conclusion: Most of the granuloma are of infective origin and tubercular granuloma is most common type of etiology in biopsies which shows granulomatous inflammation and lymphnode is the most common affected site.

Key words: Granulomatous inflammation, Tuberculosis, Histopathological examination, ZN staining.

Doi : 10.18231/2581-3706.2018.0052

How to cite : Shrivastava A , Maru A M , Choksi T S , Agnihotri A S , A five year histopathological study of granulomatous lesions at a tertiary care centre. IP J Diagn Pathol Oncol 2018;3(4):253-256

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (