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Indian Journal of Pathology and Oncology

Histopathological study of tumours of bones and joints

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Author Details : Gururajaprasad C, Damodaran A. M

Volume : 6, Issue : 1, Year : 2019

Article Page : 16-24

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Introduction: Tumours of Bones & joints are rare. The histogenesis of some of these is still uncertain. Unpredictable behaviour of undifferentiated tumours and some of the differentiated tumours, are a challenge.
Aims and Objectives: Cases of tumours of bones & joints were studied for their varied Histopathology. Tumour like conditions were not included.
Materials and Methods: Biopsies of 74 Patients with tumours of Bones & joints, admitted to J.S.S. Medical College Hospital and Dental College Hospital, from April 2015 to April 2018 were studied. Cases were clinically & radiologically examined & studied by routine Haematoxilin & Eosin stains after decalcification by 10% formic acid. Special stains & I.H.C were done when required.
Results: In this study, benign tumours of bone were 56.25% & Malignant were 43.75 %. Joints infiltrated by synovial sarcoma was 8.10%. Benign odontogenic tumours were 5.4% & malignant tumours were 6.75%. Male to female ratio in benign tumours was 2.65:1 & in malignancy, 1.35:1. Sex incidence of the commonest malignant tumour osteosarcoma was to 1: 1. Next commoner malignancy was synovial sarcoma infiltrating the joints with a sex ratio of 1:5. Giant cell tumours showed a sex ratio of 3:2.
Conclusion: Tumours of bones & joints are a real challenge to the pathologist, Radiologist & orthopedic surgeons because of their varied presentation, uncertain histogenesis in some & their behavior to treatment. A sincere effort is done to classify, study their varied histopathological features & rarities which definitely deepens our knowledge on this.

Keywords: Bone tumours, Osteosarcoma, Giant cell tumour, Joint tumours.

Doi : 10.18231/2394-6792.2019.0003

How to cite : Gururajaprasad C, Damodaran A. M, Histopathological study of tumours of bones and joints. Indian J Pathol Oncol 2019;6(1):16-24

Copyright © 2019 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (