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Indian Journal of Pathology and Oncology

Importance of Histopathology in Routine Cholecystectomies

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Author Details : Ashwini B.R., Hafsa Saif, Siddiq M. Ahmed

Volume : 4, Issue : 2, Year : 2017

Article Page : 313-317

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Introduction: Gall bladder is one of the common histopathological specimen received in pathology department during routine practice. Many a times premaligant changes, in-situ and invasive carcinomas are found as incidental findings in histopathology (HPE).
Objectives: To know the incidence of various histopathological lesions which are most of the times incidentally identified in routine and elective cholecystectomies at our institution.
Materials and Method: The study was conducted from January 2016 to June 2016. The gross specimen of gall bladder was received for histopathological examination at department of pathology. Gross examination findings of the specimen were recorded. If any calculi were present, their type and number were documented. Eight bits were sampled with 4 bits in one capsule.
Results: 107 gall bladder specimens were received during the study period. A female preponderance was seen in our study with male to female ratio of 1:2.2. Majority of the cases seen were between 31-40 yrs. 97.3% cases were non neoplastic lesion and 2.7% were neoplastic. 18 cases had metaplasia, out of which 13 cases (12.1%) showed antral type metaplasia, 2 cases (1.9%) of intestinal metaplasia and 3 cases (2.8%) with both antral and intestinal type metaplasia was seen. One case of biliary intra epithelial neoplasia grade II (0.9%), one case of biliary adenoma (0.9%) and one case of invasive adenocarcinoma of gall bladder (0.9%) were incidentally identified.
Conclusion: Although most of the cholecystectomies are elective done for cholecystitis a varied histopathological types of the lesions can be seen in gall bladder. Thus a meticulous and detailed examination of both gross and microscopy by sampling more bits is essential. Hence routine histopathological examination is gold standard and is mandatory for all cholecystectomy specimens.

Cholecystitis, Metaplasia, Carcinoma, Routine HPE

How to cite : B.r. A, Saif H, Ahmed S M, Importance of Histopathology in Routine Cholecystectomies. Indian J Pathol Oncol 2017;4(2):313-317

Copyright © 2017 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (