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Indian Journal of Pathology and Oncology

Study of Genitourinary malformations in perinatal autopsies

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Author Details : Shailaja A. Kupati, Anita A. M, Anuradha G. Patil, Sainath K. Andola

Volume : 4, Issue : 2, Year : 2017

Article Page : 254-259

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Introduction: Congenital malformations remain a common cause of perinatal deaths and even though ultrasonography can give fairly accurate diagnosis, perinatal autopsy is essential to confirm the diagnosis and look for associated malformations.
Aim: To emphasize the importance of perinatal autopsy in diagnosing Genitourinary malformations.
Study Design: Retrospective analysis of cases with fetal genitourinary malformations was done. All fetuses were examined with external and internal examination and histopathological examination.
Materials and Material: Present study comprises of 200 cases of perinatal autopsies out of which 17cases of genitourinary malformations were studied.
Results: A total of 17 cases with Genitourinary malformations were studied. Most of them were renal malformations. Of all, 8 were cystic diseases of kidney, 3 cases of bilateral renal agenesis and 2 were unilateral, 1 case of urethral stenosis and 3 cases of extrophy of bladder were found. Among associated syndromes multicystic dysplasia found in Meckel gruber, Majawasky and Potters syndrome, whereas OEIS complex showed Extrophy of bladder. In Edward’s syndrome bilateral polycystic kidneys were found.
Conclusion: Even though the prenatal ultrasonography reasonably predicts the malformations, fetal autopsy is essential to look for additional malformations.

Congenital malformations, Perinatal, Autopsy, Genitourinary

How to cite : Kupati S A, Anita A. M, Patil A G, Andola S K, Study of Genitourinary malformations in perinatal autopsies. Indian J Pathol Oncol 2017;4(2):254-259

Copyright © 2017 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (