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Indian Journal of Pathology and Oncology

Histomorphological spectrum of paediatric surgical lesions: experience at a tertiary care centre

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Author Details : Seema Bijjaragi, Parismrita Borah, Omkar Puvvala

Volume : 3, Issue : 3, Year : 2016

Article Page : 397-403

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Aim: The aim of this study is to understand the profile of paediatric surgical pathology specimens in our region. There is paucity of studies on the histologic review in India.
Materials & Methods: This is a retrospective analysis of 462 cases of paediatric surgical specimens (Age group 0-12 years) in surgical pathology in a tertiary care centre encountered over a period of one and a half years.
Results: Out of 462 cases, 353(76.41%) cases belonged to acquired conditions (both Non-neoplastic and Neoplastic), and 109 (23.59%) cases belonged to congenital and developmental conditions. Males constituted 62.55% while females 37.45%. Gastrointestinal tract was most commonly affected (40.26%) followed by head & neck region (26.19%) and renal & urogenital system (15.58% each).
Among acquired conditions (Non-neoplastic and Neoplastic), the most common diagnosed condition was Appendicitis (27.19%) followed by Chronic tonsillitis (24.93%), Inguinal hernia (6.79%), Hydrocele (4.25%), Hemangioma (3.68%), Nonspecific lymphadenitis (3.39%), Empyema (2.83%), TB lymphadenitis and Juvenile polyp (2.55% each) etc. Among acquired neoplastic lesions, there were 4 cases of Wilms tumor, 4 cases of Osteochondroma, 1 case of Fibrous dysplasia, 2 cases of NHL, 1 case of Retinoblastoma, 6 cases of Lipoma and 1 case of Infantile rhabdomyosarcoma. 
Among congenital and developmental conditions, the most common condition was Hirschsprung’s disease (18.35%), Pelvic ureteric junction obstruction (11%), Meckel’s diverticulum & anorectal malformations (9.17% each), Testicular anomalies & enterogenous cyst (6.42% each) etc.
Conclusion: The histopathological patterns of surgical pathology specimens in childhood differ from adults. There are very few published reports on histopathological profile of paediatric surgical pathology specimens in India. Hence, we conducted this study to characterize the histopathological types of surgical pathology specimens among the paediatric patients.

Keywords: Paediatric, Congenital, Developmental, Acquired


How to cite : Bijjaragi S, Borah P, Puvvala O, Histomorphological spectrum of paediatric surgical lesions: experience at a tertiary care centre. Indian J Pathol Oncol 2016;3(3):397-403

Copyright © 2016 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (