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IP International Journal of Orthopaedic Rheumatology


Spondyloarthropathy: A critical management analysis


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Research Article

Author Details : Shiva Shankar Jha*

Volume : 5, Issue : 2, Year : 2019

Article Page : 42-54


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Abstract

Spondyloarthropathy, a group of overlapping disorders of chronic inflammatory diseases of autoimmune nature has undergone critical changes in its management, specially with introduction of newer biologics and targeted synthetic DMARDs. Secukinumab and Tofacitinib are newer additions to proper management targeting various cytokines. Cost being an important factor in developing world, conventional synthetic DMARDs are being advocated to be used in situations where patient can not afford the treatment with biologics / small molecules i.e. JAK Inhibitors. It is heartening to know that methotrexate can achieve 20% remission in psoriatic arthritis almost equivalent to some biologics. Drug antibody is also a challenging problem in management with biologics.

Keywords: Biologic, DMARDs, Secukinumab, Tofacitinib, JAK Inhibitors, Cost.

Doi : 10.18231/j.ijor.2019.010

How to cite : Jha S S, Spondyloarthropathy: A critical management analysis. IP Int J Orthop Rheumatol 2019;5(2):42-54

Copyright © 2019 by author(s) and IP Int J Orthop Rheumatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)