Article Access statistics

Viewed: 618

Emailed: 0

PDF Downloaded: 175

Indian Journal of Obstetrics and Gynecology Research

Fetomaternal Outcome in Acute Viral Hepatitis

Full Text PDF Share on Facebook Share on Twitter

Author Details : Pooja Gupta Jain, Shilpa Sapre

Volume : 3, Issue : 3, Year : 2016

Article Page : 264-266

Suggest article by email


Introduction: Viral hepatitis is one of the commonest causes of jaundice in pregnancy. Hepatitis E viral (HEV) infection is associated with major catastrophes in pregnancy with high maternal and foetal mortality rate.
Objectives: To determine the prevalence of HEV infection in pregnancy and to study maternal and foetal outcome in acute HEV and non HEV infection.
Material and Methods: This was a prospective observational study, conducted at SAIMS obstetrics department over a period of 2 years, June 2011-June 2013, among pregnant women presented with features of acute viral hepatitis like nausea, vomiting, jaundice, fever etc. These women were further investigated and those who were found to be positive for infection with HAV, HBV and HEV were further studied in view of maternal and foetal outcome.
Results: Pregnant women who were found to be suffered from acute viral hepatitis were twenty five. Majority of women were unbooked (90%) with mean age of 23±3.5years, most of them were presented in third trimester with mean gestational age of 31.33±3.5 weeks. Primigravida (58%) forms the largest group. Infective pathology due to HEV was 84% and 16% due to HAV and none of the patients were found to be acutely infected with HBV, HCV. HEV infected patients found to have high rate of complications as compared to non HEV infected patients. HEV infected patients had high rate of abortion (4.7%), fulminant hepatic failure (23.8%), Disseminated intravascular coagulation (33%), acute respiratory distress syndrome (14.28%), hepatic encephalopathy (23.8%), acute renal failure (9.52%), intrauterine foetal demise (35.29%), low birth weight (84.6%), NICU admission rate and preterm labour as compared to non HEV infected patients.
Conclusion: Acute hepatitis E viral infection in pregnancy carries a poor maternal and foetal outcome as compared to other viral hepatitis causative agents.

Hepatitis, HEV infection

How to cite : Jain P G, Sapre S, Fetomaternal Outcome in Acute Viral Hepatitis. Indian J Obstet Gynecol Res 2016;3(3):264-266

Copyright © 2016 by author(s) and Indian J Obstet Gynecol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (