Print ISSN:-2394-546X

Online ISSN:-2394-5478


Current Issue

Year 2020

Volume: 7 , Issue: 2

Article Access statistics

Viewed: 787

Emailed: 0

PDF Downloaded: 477

Indian Journal of Microbiology Research

Carbapenem –resistant Enterobacteriaceae : Prevalence and bacteriological profile in a tertiary teaching hospital from rural western India

Full Text PDF Share on Facebook Share on Twitter

Author Details : Satyajeet K Pawar*, S T. Mohite, R V. Shinde, S R. Patil, G S. Karande

Volume : 5, Issue : 3, Year : 2018

Article Page : 342-347

Suggest article by email


Introduction: In last few years, Gram-negative bacilli are isolated capable of producing various classes of carbapenemases with ability of hydrolyzing the ?-lactam antimicrobial. Carbapenem Resistant Enterobacteriaceae (CRE) have been reported worldwide. There is a serious threat to public health due to the emergence and rapid spread of CRE.
Aims: To find prevalence and bacterial profile of CRE in clinical isolates in indoor patients from a rural tertiary care centre.
Materials and Methods: The study was conducted in a tertiary care teaching hospital in Western India, June 2016 to April 2018. The clinical specimens received in microbiology laboratory were processed by the standard method. Bacteria were identified by VITEK 2 compact (Biomerieux) automation system, and antimicrobial susceptibility testing was done with the same system to detect minimum inhibitory concentrations for carbapenem group of antimicrobials. CLSI 2016 guidelines were used to detect CRE.
Results: Total 535 Enterobactericaeae clinical isolates were included in the study. Of these, 31.77% (n=170) were CRE. Specimens like urine, pus/ wound swab and endotracheal tube secretion were the major contributors for CRE isolates.82% of CRE were Klebsiella pneumoniae (63%) and E.coli (19%).
Conclusions: A high prevalence of 31.77% carbapenem resistance was observed among Enterobacteriaceae isolates. Early detection, isolation and contact precaution of CRE patients will help to prevent rapid dissemination of CRE infection.

Keywords: Carbapenem Resistant Enterobacteriaceae, CRE, Carbapenemase, Klebsiella pneumoniae.

Doi : 10.18231/2394-5478.2018.0072

How to cite : Pawar S K, Mohite S T, Shinde R V, Patil S R, Karande G S, Carbapenem –resistant Enterobacteriaceae : Prevalence and bacteriological profile in a tertiary teaching hospital from rural western India. Indian J Microbiol Res 2018;5(3):342-347

Copyright © 2018 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (