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Indian Journal of Microbiology Research


Microbiological profile of abnormal vaginal discharge and its antimicrobial susceptibility pattern in a Tertiary Care Hospital, Gujarat


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Author Details : Vaidehi J. Mehta, Sanjay J. Mehta

Volume : 4, Issue : 3, Year : 2017

Article Page : 308-315


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Abstract

Introduction and Objective: Abnormal vaginal discharge is associated with adverse pregnancy outcomes, increase morbidity and mortality with emergence of widespread resistance to antimicrobials. The knowledge of the causative agents of abnormal vaginal discharge will be helpful in the selection of empiric antimicrobial therapy. The present study was conducted to isolate and identify the pathogens associated with abnormal vaginal discharge and to find out its antibiotic susceptibility pattern.
Materials and Method: Total 400 cases complaining of abnormal vaginal discharge were studied, between the age group of 15-50 years during period of August 2012 to June 2014 in CUSMC Microbiology Department, Gujarat. Samples were processed as per standard guidelines.
Results: Out of 400 samples, 191 (47.8%) yielded growths of organisms. From this 174 (91.09%) were monomicrobial, while 17 (8.9%) were polymicrobial making a total of 208 isolates. Common isolated infections include, Vulvovaginal Candidiasis (54.3%), followed by Aerobic Vaginitis (37.9%), Bacterial vaginosis (4.80%) and Trichomonas vaginalis (2.88%). Prevalence of ESBL Production was 26.6% for Klebsiella sp. and 47% of E.coli were ESBL producers. C. albicans showed 87.9% sensitivity towards Fluconazole and 90.3% to Voriconazole. Among non albicans species C. krusei showed totally resistance to Fluconazole and 70% sensitivity to Voriconazole.
Conclusion: Incidence of abnormal vaginal discharge was 47.8%. Vulvovaginal Candidiasis most commonly caused by C. albicans (73.4%). Aerobic vaginitis is most commonly caused by E.coli (41.7%) Most isolates were multidrug resistance.

Keywords:
Abnormal vaginal discharge, Pathogens, Adverse pregnancy outcomes, Multidrug resistance organisms, Antimicrobial sensitivity pattern

 

How to cite : Mehta V J, Mehta S J, Microbiological profile of abnormal vaginal discharge and its antimicrobial susceptibility pattern in a Tertiary Care Hospital, Gujarat. Indian J Microbiol Res 2017;4(3):308-315

Copyright © 2017 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)