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IP International Journal of Medical Paediatrics and Oncology


Lennox gastaut syndrome- A case report and review of treatment protocol


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Review Article

Author Details : Poonam Prakash*, S K Bhandari, Manab Kosala

Volume : 6, Issue : 1, Year : 2020

Article Page : 5-9


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Abstract

Lennox-Gastaut syndrome (LGS) is a severe pediatric epilepsy syndrome characterized by mixed seizures, cognitive decline, and generalized slow (<3Hz>Seizures are often resistant to therapy. Atonic seizures result in dangerous drop attacks with risks of injury and impairment of the quality of life. The seizures are frequently resistant to multiple antiepileptic (AED) drugs. The non pharmacological treatments such as the ketogenic diet, vagus nerve stimulation, and epilepsy surgery should be considered when multidrug therapy is of  limited  help.

This paper aims to present a case report along with an updated comprehensive outline of LGS and the available medical, surgical and dental treatments. Further long term randomized controlled trials are required to compare efficacy of different therapeutic interventions.

Keywords: Lennox Gataut syndrome, Pediatric epilepsy, Ketogenic diet.


Doi : 10.18231/j.ijmpo.2020.002

How to cite : Prakash P, Bhandari S K, Kosala M, Lennox gastaut syndrome- A case report and review of treatment protocol. IP Int J Med Paediatr Oncol 2020;6(1):5-9

Copyright © 2020 by author(s) and IP Int J Med Paediatr Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)