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Indian Journal of Clinical and Experimental Ophthalmology

Tear film changes in diabetic retinopathy: A hospital based case control study

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Research Article

Author Details : Anupama C Shetgar, Vrinda Viswanathan*, Brijesh A Patil, K R Kulkarni, Hamsa D S

Volume : 6, Issue : 2, Year : 2020

Article Page : 252-255

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Aim: To compare the tear film changes in diabetic population with and without diabetic retinopathy.
To study the association of dry eye with different gradings of diabetic retinopathy.
Materials and Methods: A case control study was conducted in 112 eyes in diabetics with and without
diabetic retinopathy changes. Tests for tear film changes like Schirmers, TBUT and KES was conducted
and the results were compared.
Results: The mean value of Schirmer in diabetic retinopathy group was 10.84 +/- 4.785, mean value
of TBUT was 7.73+/- 2.908 and that of KES was 1.34 +/- 0.745 whereas mean value of Schirmers in
non DR group was 12.84+/- 2.947, that of TBUT was 10.43+/- 2.035 and that of KES was 0.73+/- 0.726.
Significantly poorer Schirmers (p= 0.009), TBUT (p=0.001) and KES(p=0.001) was found in the DR group.
Conclusion: With increasing severity of diabetic retinopathy these signs and symptoms of dry eye have
found to increase thereby a significant association between dry eye and grading of DR.

Keywords: Tear film, Keratoepitheliopathy score, Diabetic retinopathy, Tear film break up time, Schirmers.

Doi : 10.18231/j.ijceo.2020.054

How to cite : Shetgar A C, Viswanathan V , Patil B A, Kulkarni K R, Hamsa D S, Tear film changes in diabetic retinopathy: A hospital based case control study. Indian J Clin Exp Ophthalmol 2020;6(2):252-255

Copyright © 2020 by author(s) and Indian J Clin Exp Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (