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IP Indian Journal of Clinical and Experimental Dermatology

Study on serum copper, zinc and selenium trace element levels in Psoriasis

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Original Article

Author Details : Vijaya Mohan Rao*, M Deepthi, K Ramalingam, M Prasad Naidu, Mahaboob V. Shaik

Volume : 5, Issue : 3, Year : 2019

Article Page : 239-242

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Introduction: Psoriasis is one of the skin disorder, mainly characterized by scaly papules and plaques. The
etiology of psoriasis is multifactorial and still not properly understood. In our study, we tried to elucidate
the relation between psoriasis and trace elemens namely Zinc, Copper and Selenium.
Materials and Methods: This study enrolled 50 psoriasis patients with 37 males and 13 females, with 10-
80 years age. The patients were randomly selected from the outpatient clinic of Dermatology, Venereology
and Leprosy Department, Narayana medical college and hospital. The age, sex matched 50 healthy
volunteers included as controls in this study. Levels of serum Copper (Cu), Zinc(Zn), and Selenium(Se)
analysed using Atomic absorption Spectrophotometery.
Results: In our study, the mean Serum Zinc, Selenium and Copper levels were 61.968015.96824,
64.206017.44780 and 56.41208.51976 respectively, lower than the controls which was stastically
significant (P<0> Conclusion: In psoriasis, serum Cu, Zn and Se levels were observed to be low, needs to manage
therapeutically by oral supplementation. More studies are required to carryout to standardize the diagnostic
levels of Cu, Zn and Se and their role in psoriasis pathogenseis.

Keywords: Psoriasis, Zinc, Copper, Selenium P Value 0667 0266.

Doi : 10.18231/j.ijced.2019.051

How to cite : Rao V M, Deepthi M, Ramalingam K, Naidu M P, Shaik M V, Study on serum copper, zinc and selenium trace element levels in Psoriasis. IP Indian J Clin Exp Dermatol 2019;5(3):239-242

Copyright © 2019 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (