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IP Indian Journal of Clinical and Experimental Dermatology


Impact of psoriasis on serum lipid profile, CRP, ADA: A controlled study of 25 patients


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Author Details : Rita Vora, Nishit Surti, Rahul Krishna Kota, Trusha Patel, Khushboo Modasia

Volume : 4, Issue : 3, Year : 2018

Article Page : 246-249


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Abstract

Introduction: Psoriasis is a chronic disorder with certain systemic compounds. It has been associated with increase in morbidity and mortality from cardiovascular events especially in chronic cases.
Aims and Objectives: To compare the levels of CRP, S.ADA and S. Lipid profile among psoriatic patients and controls.
Materials and Methods: This is a cross sectional case control study conducted in department of dermatology for a period of 6 months in a teaching institute of Gujarat. Cases included patients of psoriasis attending skin OPD. Controls were taken from health check-up scheme of our hospital with minimal confounding factor. CRP, S.ADA and S. Lipid profile were assessed in both groups.
Statistical Analysis: We applied Unpaired T- test for statistical analysis and p value < 0> Results: Patient and control group consisted of 25 subjects each. Serum CRP, serum cholesterol and serum TG levels were found to be more significantly elevated in cases when compared to controls with p-value (by unpaired t test) of 0.001, 0.026 and 0.044 respectively. Serum ADA, LDL, VLDL was high among cases when compared to controls but were not statistically significant. (p>0.05).
Conclusion: patients of psoriasis have to be evaluated for risk factors of atherosclerosis like Serum lipid profile, CRP.

Keywords: Psoriasis, CRP, ADA, Lipid profile.

Doi : 10.18231/2581-4729.2018.0052

How to cite : Vora R, Surti N, Kota R K, Patel T, Modasia K, Impact of psoriasis on serum lipid profile, CRP, ADA: A controlled study of 25 patients. IP Indian J Clin Exp Dermatol 2018;4(3):246-249

Copyright © 2018 by author(s) and IP Indian J Clin Exp Dermatol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)