Print ISSN:-2581-9534

Online ISSN:-2581-8988

Current Issue

Year 2020

Volume: 5 , Issue: 3

Article Access statistics

Viewed: 658

Emailed: 0

PDF Downloaded: 210

IP Indian Journal of Conservative and Endodontics


Comparison of the effect of two MMP inhibitors on microtensile bond strength to dentin in class I cavities


Full Text PDF Share on Facebook Share on Twitter


Author Details : Rahul J., T. S. Vinoth Kumar, Deivanayagam Kandaswamy, Manuja Nair, Aparna Ramachandran

Volume : 3, Issue : 2, Year : 2018

Article Page : 40-43


Suggest article by email

Abstract

Aim: To compare the effects of pretreatment with doxycycline and chlorhexidine on microtensile bond strength to dentin in class I cavities restored with composite resin.
Materials and Methods: Class I cavities were prepared on the occlusal surface of 30 freshly-extracted caries-free molars. In group 1, 2% chlorhexidine was applied to the acid etched surface, placed in contact for 20 seconds, and gently air dried without rinsing. In group 2, 2% doxycycline was applied to the acid etched surface, placed in contact for 20 seconds, and gently air dried without rinsing. In group 3, the control group, just the conventional bonding procedure was used without any pre-treatment. The cavities were restored with resin composite using a bulk method. After thermocycling, the specimens were serially sectioned to obtain resin dentin sticks with a rectangular cross-sectional area of approximately 1mm2 using microtome. The microtensile bond strength values were tested using Universal testing machine at crosshead speed of 0.5 mm/min until failure. The results obtained were analyzed by One-way ANOVA and Tukey's HSD tests for statistical significance.
Results: The pre-treatment with chlorhexidine and doxycycline showed a significant effect in preserving the in vitro bond strength, when compared to the control group (p=0.000). Among the test groups, the chlorhexidine treatment resulted in a higher bond strength value than doxycycline group (p=0.000).
Conclusion: Pre-treatment with MMP inhibitors resulted in higher bond strength values. Chlorhexidine group showed a significantly higher bond strength value compared to the Doxycycline group.

Keywords: Chlorhexidine, Dentin, Doxycycline, MMP inhibitors, Microtensile bond strength

Doi : 10.18231/2456-8953.2018.0011

How to cite : Rahul J., Kumar T S V, Kandaswamy D, Nair M, Ramachandran A, Comparison of the effect of two MMP inhibitors on microtensile bond strength to dentin in class I cavities. IP Indian J Conserv Endod 2018;3(2):40-43

Copyright © 2018 by author(s) and IP Indian J Conserv Endod. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)