Print ISSN:-2394-6369

Online ISSN:-2394-6377

CODEN : IJCBK6

Current Issue

Year 2020

Volume: 7 , Issue: 2

Article Access statistics

Viewed: 407

Emailed: 0

PDF Downloaded: 158

International Journal of Clinical Biochemistry and Research


Serum ischemia modified albumin as a potent biochemical marker in pre-eclampsia patients attending a tertiary care hospital in central India


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : Navanil Roy*, Sahana Sahana

Volume : 6, Issue : 2, Year : 2019

Article Page : 209-212


Suggest article by email


Abstract

Introduction: Pre-eclampsia (PE) a pregnancy specific disease, the most common cause of fetal and maternal death yet, no specific prevention and treatment is available. Reliable biochemical markers for prediction and diagnosis of PE can have a better impact on maternal health and several of these markers have been suggested till now. Recently Ischemia Modified Albumin (IMA) has emerged as a marker in different diseases, where ischemia is the origin or consequence behind disease pathology.
Materials and Methods: 30 patients with PE were selected for the study and compared with 30 pregnant healthy controls. IMA IMA/albumin with other routine biochemical markers was estimated in these patients.
The results were then statistically analysed.
Results: IMA levels were found significantly raised in PE patients as compared to normal pregnant controls (p value<0 r=+0.3> Conclusion: IMA generated by hypoxia/ischemia driven oxidative stress is also raised in PE, hence can be used as a biomarker in PE. Further studies are needed to establish the relationship between IMA, disease process and its association with severity of the disease.

Keywords: Pre-eclampsia, Ischemia Modified albumin.

Doi : 10.18231/j.ijcbr.2019.046

How to cite : Roy N, Sahana S, Serum ischemia modified albumin as a potent biochemical marker in pre-eclampsia patients attending a tertiary care hospital in central India. Int J Clin Biochem Res 2019;6(2):209-212

Copyright © 2019 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)