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Volume: 7 , Issue: 2

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International Journal of Clinical Biochemistry and Research

Secondary hyperparathyroidism in patients with chronic kidney disease: A case control study

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Research Article

Author Details : Jyothi A Natikar*, A Shailaja

Volume : 7, Issue : 2, Year : 2020

Article Page : 291-296

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Introduction: Secondary hyperparathyroidism is a major complication of Chronic kidney disease resulting
from disturbances in the regulation of Parathyroid hormone, calcium, phosphorus and vitamin D. Adding to
the burden of CKD elevated Parathyroid hormone levels are responsible for the long-term consequences like
renal osteodystrophy, vascular calcifications and also contributes to cardiovascular morbidity and mortality
among end-stage renal disease patients. Hence, this study was conducted to correlate the levels of PTH in
patients with CKD in comparison to normal healthy controls.
Materials and Methods: 54 patients diagnosed as CKD and 46 healthy controls are included in the study.
Serum levels of Urea, creatinine & PTH measured in both cases and controls.
Results : Statistically significant increase in PTH levels were observed in cases as compared to controls
(p<0> Conclusion: An increase in PTH levels is seen as the disease progressed. Thus, periodic measurement of
PTH is recommended in all patients with CKD in order to reduce complications.

Keywords: Secondary hyperparathyroidism (SHPT), Chronic kidney disease (CKD), Parathyroid hormone (PTH).

Doi : 10.18231/j.ijcbr.2020.063

How to cite : Natikar J A, Shailaja A , Secondary hyperparathyroidism in patients with chronic kidney disease: A case control study. Int J Clin Biochem Res 2020;7(2):291-296

Copyright © 2020 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (