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International Journal of Clinical Biochemistry and Research

Impact of thermal injury on liver function test and serum electrolytes: Its role in management

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Research Article

Author Details : Priyank Udagani*, Vibha C, H L Vishwanath

Volume : 6, Issue : 4, Year : 2019

Article Page : 553-557

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Burn is a wound in which there is coagulative necrosis of the tissue. Various metabolic and biological
changes follow burn injury. Thermal injury results in significant pathophysiological changes by interplay of
various mediators in early stages. These changes further exacerbate the whole body inflammatory response
into vicious cycle of accelerating organ dysfunction.
Aim: The aim of the study is to evaluate the Liver Function Test and Serum Electrolytes in burn patients
and its role in management of patient.
Materials and Methods: The study was done on 50 burn inpatients and 50 healthy persons taken as
controls from Mahabodhi Burns Critical Centre (MBCC), Victoria Hospital attached to Bangalore Medical
College and Research Institute, Bangalore.
Results: There is strongly significant difference in serum Total bilirubin, Direct Bilirubin, Total protein,
Albumin, ALT, Sodium, Chloride between cases and controls (<0> difference between AST, and potassium (<0> Conclusion: Liver plays a central role in burn injury and postburn outcome. Restoration of liver function
especially albumin helps in better treatment of patients and decrease the mortality. Measurement of serum
sodium is not only a means of diagnosing dehydration but it is good guide for estimating and managing
ongoing fluid loss. Hyperkalemia should be managed in order to prevent cardiovascular effects. Burn
represents devastating injury affecting nearly every organ system and leading to significant morbidity and

Keywords: Burns, Hypoalbuminemia.

Doi : 10.18231/j.ijcbr.2019.115

How to cite : Udagani P, Vibha C, Vishwanath H L, Impact of thermal injury on liver function test and serum electrolytes: Its role in management. Int J Clin Biochem Res 2019;6(4):553-557

Copyright © 2019 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (