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Indian Journal of Clinical Anatomy and Physiology

Study of pulmonary function test in hypothyroidism

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Author Details : Bemat Ilyas Yaqub, Mohammed Suhail, Amarnath Baswantrao Solepure, Badar Azhar Daimi, Bemat Ishrat Fa

Volume : 5, Issue : 3, Year : 2018

Article Page : 394-396

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Introduction: thyroid disorders are very common worldwide and there is steep rise in thyroid disorders in India as well.1 There are very few studies done in past to evaluate effect of thyroid disorder on pulmonary function. This study is focused on estimating effects of hypothyroidism on pulmonary function of affected individual.
Aim: To study pulmonary function test in hypothyroid patients and to assess correlation of compromised pulmonary function with Thyroid stimulating hormone levels, duration of hypothyroidism, age of patient and body mass index values.
Materials and Methods: A total of 67 hypothyroid patients were selected. This study was approved by the Ethical Committee. The present study was carried out in accordance with the Helsinki declaration all participants participated voluntarily after being given a detailed explanation of the purpose of the study. All hypothyroid patients visiting medicine OPD and those hospitalised were included in study. Smokers, former smokers, patients suffering from lifestyle disease and all patients suffering from pulmonary diseases were excluded from study. Pulmonary function tests were evaluated by computerised spirometer HELIOS 702 of recorders and medicare systems private limited (RMS). Data so obtained was analysed with the help of SPSS.
Results: both FVC and FEV1 means were decreased. 44% of patients were having restrictive type of lung disease. Forced vital capacity (FVC) and forced expiratory volume in one sec (FEV1) showed strong negative correlation with Thyroid stimulating hormone levels (TSH), duration of hypothyroidism and Body mass Index (BMI).
Conclusion: Findings of this study were consistent with restrictive type of lung disease in hypothyroid patients. Hypothyroidism compromises the pulmonary function of affected individual to variable degree depending upon duration of disease and higher levels of TSH and BMI. All hypothyroid patients must be screened for abnormalities of pulmonary function and all patients with impaired pulmonary function must be screened for thyroid function test to detect and prevent adverse outcomes.

Keywords: Hypothyroidism, Forced vital capacity, Pulmonary function test, TSH, BMI, Duration of disease.

Doi : 10.18231/2394-2126.2018.0091

How to cite : Yaqub B I, Suhail M, Solepure A B, Daimi B A, Bemat Ishrat Fa, Study of pulmonary function test in hypothyroidism. Indian J Clin Anat Physiol 2018;5(3):394-396

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