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Indian Journal of Clinical Anaesthesia


A randomized controlled study of intraperitoneal vs intraincisional infiltration of local anesthetic levobupivacaine for pain relief in post-laparoscopic hysterectomy cases


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Author Details : Gopal Reddy Narra, Manohar, Aiswarya, Amit Kumar, Monica Krishna

Volume : 4, Issue : 3, Year : 2017

Article Page : 316-319


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Abstract

Introduction and Aim: Providing postoperative pain relief is a common acceptable practice in modern era. Multimodal combination methods are being used to reduce opioid-related side effects. We conducted a randomized study with 0.125% levobupivacaine in intraincisional infiltration vs intraperitoneal instillation for pain relief after laparoscopic hysterectomies.
Materials and Method: In this randomized controlled study 90 patients of laparoscopic hysterectomy were selected. They were grouped as Group-C the control placebo, Group-I received local wound infiltration (intraincisional) of 20 ml solution of 0.125%, levobupivacaine while Group-P received 20 ml solution of 0.125%, levobupivacaine intraperitoneal space. Recording of post-surgical pain from 0 to 24 hours along with nausea and vomiting was done.
Results: Post-operative pain was significantly lower and requirement butorphanol also less in intraincisional infiltration of 0.125% levobupivacaine in group -I (300±470µg)when compared to group-C and P (950±223, 600±502) in 1st 4 hours with significant p -value 0.000041 and in 24 hours group-C{783.33±415.45} group-I {466.67±503.09} and group-P {583.33±457.18} with significant p-value of 0.0013. Regarding opioid requirement in 1st-4 hours in group-C (90%) group-I only (30%) and group-P (60%), in 8-24 hours period in group-C (60%) compared to group-I(40%) and group-P(50%).
Conclusion: Incisional infiltration of levobupivacaine is more effective than intraperitoneal instillation in controlling the post-operative pain.

Keywords:
Laparoscopic hysterectomy, Levobupivacaine, Local anesthetic, Post-operative pain Intraincisional infiltration, Intraperitoneal instillation

How to cite : Narra G R, Manohar, Aiswarya, Kumar A, Krishna M, A randomized controlled study of intraperitoneal vs intraincisional infiltration of local anesthetic levobupivacaine for pain relief in post-laparoscopic hysterectomy cases. Indian J Clin Anaesth 2017;4(3):316-319

Copyright © 2017 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)