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Indian Journal of Clinical Anaesthesia

Propofol or etomidate: Does it genuinely matter for induction in cardiac surgical procedures?

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Author Details : Manjunath Ratnakara Kamath, Suchitha Kamath, Krishna Prasad Patla

Volume : 3, Issue : 4, Year : 2016

Article Page : 551-555

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In the present study we compared propofol with etomidate in cardiac surgical procedures, in order to determine suitability of each agent for induction.
Aims:  To compare propofol with etomidate with respect to hemodynamic stability during induction of anesthesia.
Settings and design: This prospective randomized study was carried out on 60 patients admitted for open cardiac surgical procedures.
Methods: The patients undergoing elective cardiac surgeries both on pump and off pump surgeries were randomly assigned to one of the two study groups, each group consisting of 30 patients.
Statistical analysis: The observations in both the groups were recorded. Statistical analysis was done using SPSS version 20, student’s t test and chi square test.
Results: Fall in heart rate was more in propofol group. Hemodynamic stability was better in etomidate group.
Conclusion: Etomidate is a better agent in cases with limited cardiac reserve when compared to propofol. However both agents can be appropriate for induction of anesthesia in cardiac surgical procedures, if given judiciously.

: Anesthesia, Propofol, Etomidate, Cardiac surgery

How to cite : Kamath M R, Kamath S, Patla K P, Propofol or etomidate: Does it genuinely matter for induction in cardiac surgical procedures?. Indian J Clin Anaesth 2016;3(4):551-555

Copyright © 2016 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (