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Indian Journal of Clinical Anaesthesia

“A prospective clinical study of 0.5% levobupivacaine with 0.5% bupivacaine in spinal anaesthesia”

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Author Details : Ramakrishna Reddy Mudiganti, Swathi K, Aruna Subhash T

Volume : 3, Issue : 3, Year : 2016

Article Page : 411-422

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Background: Spinal anaesthesia is a popular technique for lower abdominal surgeries for more than a century. Choice of local anaesthetics depends mainly onset, duration, intensity of sensory and motor block and side effects. With time newer local anaesthetics were invented and used to get better analgesia and less side effects.
Aim: To study and compare the effects of 0.5% Levobupivacaine with 0.5% Bupivacaine in spinal anaesthesia.
Design: Randomised Controlled study.

Material & Method: The study includes 100 patients randomly divided into 2 groups of 50 each. Group L patients received 3ml of 0.5% Levobupivacaine (15mg) 5mg/ml.Group B patients received 3ml of 0.5% Bupivacaine (15mg) 5mg/ml.
Statistical Analysis: by using SPSS version 20 (Statistical Package for Social Studies), Chi square test, F table, Mean and standard deviation were used.
Results & Conclusion: Duration of sensory block and time for first requirement of post-operative analgesia was longer in patients who received 0.5% Levobupivacaine intrathecally when compared to 0.5% Bupivacaine intrathecally. Though there was no statistical significance in terms of onset of sensory and motor block, duration of motor block was less in Levobupivacaine group. Stable haemodynamics and less side effects were observed with Levobupicaine. Hence, Levobupivacaine is a better alternative to Bupivacaine for spinal anaesthesia

How to cite : Mudiganti R R, Swathi K, Aruna Subhash T, “A prospective clinical study of 0.5% levobupivacaine with 0.5% bupivacaine in spinal anaesthesia”. Indian J Clin Anaesth 2016;3(3):411-422

Copyright © 2016 by author(s) and Indian J Clin Anaesth. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (