It gives me immense pleasure to present this book entitled ‘Basics of Immunology’ to the learners of immunology containing updated knowledge of the topic. Immunology is a very vast subject, interesting but sometimes frustrating when not understood properly. It is our earnest hope that style of presentation will definitely bring pleasure and comprehension to our many readers at the undergraduate, postgraduate, and clinical stages of their studies. The language is consistent, interesting, and easy to understand. It is unique in the sense that a no of concepts especially crucial to the students to understand in other foreign and Indian books on the topic have been presented in a way so that they can easily grasp with firm understanding without any confusion. Figures summarize important ideas and presented in such a way so that along with written text, the concepts are nicely conveyable to the readers. In order to visualize the complex relationship of immune system components, iconic depictions are consistently given throughout the book, in the form of tables and figures. Explanation of antigen presentation expanded discussion on MHCs and cytokines, and inflammation has been nicely explained. Expanded coverage of infection and diseases, AIDS, Autoimmune diseases, Hypersensitivity reactions, has also been done. Especial focus has been given on signalling pathways leading to maturity, differentiation, and activation of a variety of cell types. Chapter 1- Introduction part, sheds light on the concept of immunology, its historical perspective including changes undergone in the last few decades, and a broad classification of immunology with the deliberate explanation of various components of the immune system. Extensive coverage of the innate immune system its various components including a variety of defense cells, mechanistic aspects, and its interaction with adaptive immune response has been done in chapter 2. Similarly, chapter 3 concerns a great expansion of knowledge on adaptive immune response including various cell types T and B cells, their growth and differentiation, MHC class molecules, cluster differentiation factors, mechanistic aspects of humoral and cell-mediated immunity, etc. Chapter 4 focuses on the clinical aspects of immunology including disorders of lymphoid and myeloid cell lineage, hypersensitivity reactions, and AIDS. Autoimmune diseases their concept, types their utility are deliberately presented in chapter 5. The scope of immunology in medicine has been comprehensively discussed in chapter 6. In this segment, a comprehensive discussion has been done on vaccination and organ transplant, and HLA typing. Chapter 7 deals with various aspects of cancer immunology with a special focus on chimeric antigen receptor-T cells. In chapter 8 various Immunological techniques broadly cover the experimental protocols to investigate the immune system as well as the procedures of creating and utilizing immunological materials as the experimental tools. Chapter 9 is dealing with various aspects of stem cell applications and therapeutics. With all these aforesaid contents, I hope that style of presentation will definitely bring pleasure and proper understanding to our many readers at the undergraduate, graduate, and clinical stage of their studies. Thanks.
Dr. Preeti Sharma
Motivating and talented Biochemistry Associate Professor, driven to inspire students to pursue academic and personal excellence. Consistently strive to create a challenging and engaging learning environment in which students become lifelong learners. Exceptional track record of research success with multiple published articles. Dr. Preeti Sharma is currently working as Associate Professor, Department of Biochemistry, Santosh Deemed to be University, Ghaziabad, NCR, Delhi, India, deeply involved in teaching and research. Her area of research has been interdisciplinary including Drug metabolism, Pharmacokinetics and Inflammatory markers, Immunology. She did her doctorate research from renowned world-class institute ‘Central Drug Research Institute’, Lucknow, under the aegis of (Council of Scientific and Industrial Research), New Delhi India, in the Department of Medicinal Chemistry and awarded Research Fellowship. She has more than 120 publications (research and review articles) and a few in the phase of communications with high citation. She also wrote 2 books on Bio-Organic Chemistry and Basics of Immunology. She is member of various professional bodies and has participated and presented a number of papers in National and International conferences. She is frequently invited as an International speaker and currently, she is a global cooperative research consultant. She is credited with a number of ICMR (Indian Council of Medical Research)-STS funded projects and has guided and co-guided a number of Ph.D. and MD students in the field of Biochemistry and Medical Biochemistry. Recently she is awarded the International Scientist award in 2021 and the research excellence award in 2021 for her exceptional contribution to research.
Dr. Pradeep Kumar
Dr. Pradeep Kumar is currently working as Professor of Biochemistry & Dean Students Welfare, Santosh Deemed to be University, Ghaziabad, NCR, Delhi, India, deeply involved in teaching, administration, and research. His area of research has been interdisciplinary including Cardiac Biochemistry, Biomarkers, and Immunology. He did his Doctorate research from LLRM Medical College Meerut Under the faculty of Medicine and awarded Gold Medal. He has more than 100 publications to his credit (research and review articles) and a few in the phase of communications with high citation, has participated and presented a number of papers in National and International conferences. He is also frequently invited as a National and International speaker. He co-authored the book and edited Medical Dictionary. He is a member of various professional bodies and chaired a number of scientific sessions in various conferences and CMEs. Also, he is a member and convener of various committees. He is credited with a number of ICMR (Indian Council of Medical Research)-STS funded projects and has guided and co-guided a number of Ph.D. and MD students in Medical Biochemistry. He is awarded the Outstanding Scientist award in 2021 and the Research Excellence award in 2021 for his exceptional contribution to research and development.
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